Author

Elżbieta Kierzek

Institute of Bioorganic Chemistry, Polish Academy of SciencesORCID 0000-0002-5563-003XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Bioinformatics· 1 Cancer Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Ryszard KierzekiD· 4 shared Marta Soszynska-Jozwiak· 2 shared Marta SzabatiD· 2 shared Agnieszka RuszkowskaiD· 1 shared Ai Ming Tham· 1 shared Annalisa MarsicoiD· 1 shared Artem BaranovskiiiD· 1 shared Bhavya Dhaka· 1 shared

Activity by Year

2022-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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4 shared papersCancer Biology

Ryszard KierzekORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Pan-cancer discovery of driver mutations in long noncoding RNAs reveals widespread functional rewiring of RNA regulatory elements

Sunandini Ramnarayanan, Roofiya Koya, Marta Soszynska-Jozwiak, Marta Szabat, Jack Roban, Sarang Bhutada, Bhavya Dhaka, Tilman Schaefer, Ai Ming Tham, Hugo Guillen-Ramirez, Francesca Alessandroni, Michela Coan, Artem Baranovskii, Lambert Moyon, Annalisa Marsico, , Rory Johnson

The paper identifies 121 lncRNA driver mutations across 19 cancer types using 12,631 genomes, showing mutations disrupt RNA-binding protein interactions to promote oncogenesis.

bioRxiv · Jun 12, 2026 · PreprintCancer Biology

Accurate in silico predictions of modified RNA interactions to a prototypical RNA-binding protein with {lambda}-dynamics

Murphy Angelo, Yash Bhargava, Elżbieta Kierzek, Ryszard Kierzek, Ryan L. Hayes, Wen Zhang, Jonah Z. Vilseck, Scott Takeo Aoki

This paper uses {lambda}-dynamics to predict RNA binding preferences of human Pumilio, including modified RNAs, showing high accuracy compared to experimental data.

RNA · Jul 31, 2025Peer-reviewedBiochemistry

Secondary Structure Prediction for RNA Sequences Including N6-methyladenosine

Elżbieta Kierzek, Xiaoju Zhang, Richard M. Watson, Scott D. Kennedy, Marta Szabat, Ryszard Kierzek, David H. Mathews

The paper introduces updated RNA secondary structure prediction tools and parameters for N6-methyladenosine, enabling analysis of modified RNA structures.

Nature Communications · Mar 11, 2022Peer-reviewedBioinformatics

Secondary structure of subgenomic RNA M of SARS-CoV-2

Marta Soszynska-Jozwiak, Agnieszka Ruszkowska, Ryszard Kierzek, Collin A. O’Leary, Walter N. Moss, Elżbieta Kierzek

This study determines the secondary structure of SARS-CoV-2 subgenomic RNA M through in vitro probing, revealing features important for its function and potential therapeutic applications.

Viruses · Feb 4, 2022Peer-reviewedMolecular Biology