Wendy Hanna‐Rose

This study shows that mitochondrial sirtuins sir-2.2 and sir-2.3 in C. elegans extend lifespan when fed E. coli OP50 but not HT115, with diet-dependent changes in oxidative stress gene expression.

This study uses a C. elegans model to show that adenylosuccinate lyase deficiency causes distinct neuromuscular and reproductive defects with different metabolic causes.