Peter W. Reddien

Region-stratified scRNA-seq of 607,370 cells plus 500-gene MERFISH maps adult Danionella cerebrum cell types body-wide, revealing fibroblast Hox and limb-identity programs and telencephalon regeneration dynamics.

The paper generates positional gene expression atlases for regenerative axolotl and non-regenerative mouse limbs, revealing conserved and species-specific connective tissue signatures.

This study shows planarian stem cells respond generically to injury, not specifically to the missing tissue, with varied incorporation into different tissues.

The paper creates a multimodal reference brain atlas for adult Danionella cerebrum, integrating anatomical, molecular, and functional data to study brain structure and sexual dimorphism.

This study shows that map3k1 is essential for restricting progenitor differentiation to specific locations in planarians, preventing ectopic differentiation and tumor formation.

This study shows that m6A modification is essential for planarian stem cell differentiation and tissue regeneration by regulating histone variant transcription and chromatin modifications.

This study shows that Klf4 is essential for germline and yolk cell development and regeneration from somatic stem cells in planarians.