Author

Margarita V. Pustovalova

Centre of Advanced StudiesORCID 0000-0002-5580-0553Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Anna V. SmirnovaiD· 2 shared Philipp MalakhoviD· 2 shared Sergey V. LeonoviD· 2 shared Wenyu XueiD· 2 shared Yuzhe WangiD· 2 shared DENIS V. KUZMINiD· 1 shared Julian Markovich RozenbergiD· 1 shared Nikolay S. IlyinskyiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersMolecular Biology

Anna V. SmirnovaORCID

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2 papers

Recent·Most cited

Kinetic measurements of the fluorescent protein synthesis facilitate determination of the miRNA activity.

Philipp Malakhov, Yuzhe Wang, Wenyu Xue, Zain Nofal, Nikolay S. Ilyinsky, Anna V. Smirnova, Roman N. Chuprov‐Netochin, Margarita V. Pustovalova, Sergey V. Leonov, Julian Markovich Rozenberg

The paper develops miRNA sensors using fluorescent protein synthesis to measure miRNA activity, showing faster response times compared to degradation-based methods.

bioRxiv · Dec 19, 2025 · PreprintMolecular Biology

The Small Non-coding RNA miR-16-1-3p Hampers Cancer Stem Cell Self-renewal and Invasiveness, Boosting Chemosensitivity by Adjusting TGF-β1 Signaling via MDM2/p53 Axis in Human Osteosarcoma.

Wenyu Xue, Yuzhe Wang, Anna V. Smirnova, Philipp Malakhov, Margarita V. Pustovalova, DENIS V. KUZMIN, Sergey V. Leonov

This paper shows miR-16-1-3p reduces cancer stem cell self-renewal and invasiveness in osteosarcoma by modulating TGF-β1 signaling through the MDM2/p53 axis, enhancing chemosensitivity to cisplatin.

bioRxiv · Nov 19, 2025 · PreprintCancer Biology