Author

Vincent Léguillier

AgroParisTechORCID 0000-0002-5585-2986Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:bacteria (other)· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Alexandra GrussiD· 3 shared Karine GlouxiD· 3 shared Christine PéchouxiD· 2 shared Clara Louche· 2 shared Jamila Anba‐MondoloniiD· 2 shared Paprapach WongdontreeiD· 2 shared Audrey SolgadiiD· 1 shared Bastien ProstiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersMicrobiology

Alexandra GrussORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

FabF-FadM Cooperate to Recycle Fatty Acids and Rescue ΔplsX Lethality in Staphylococcus aureus

Paprapach Wongdontree, Milya Palmier, Clara Louche, Vincent Léguillier, Carine Machado Rodrigues, Karine Gloux, David Halpern, Céline Henry, Jamila Anba‐Mondoloni, Alexandra Gruss

This paper identifies that mutations in fabF or fadM allow Staphylococcus aureus to bypass PlsX dependency by releasing fatty acids, leading to growth rescue but increased beta-lactam sensitivity.

PLoS Genetics · May 27, 2026Peer-reviewedMicrobiology

The fatty acid synthesis pathway is a checkpoint for lipoteichoic acid synthesis in Staphylococcus aureus

Paprapach Wongdontree, Clara Louche, Julien Dairou, Vincent Léguillier, Christine Péchoux, Bastien Prost, Myriam Gominet, Karine Gloux, Patrick Trieu‐Cuot, Audrey Solgadi, Alexandra Gruss, Jamila Anba‐Mondoloni

This study identifies the fatty acid synthesis pathway as a key regulator of lipoteichoic acid synthesis in Staphylococcus aureus by controlling glycerophosphate availability.

bioRxiv · Apr 7, 2026 · PreprintMicrobiology

Biotope-dependent High Level Resistance to Reactive Oxygen Species, Antibiotic Tolerance, and Virulence of Staphylococcus aureus

Vincent Léguillier, Karine Gloux, Majd Khalife, Rochelle D’Mello, Zoran Minić, Milica Sentić, Marta Catto, Marisa Manzano, Christine Péchoux, Sandrine Truchet, Philippe Gaudu, Christina Nielsen‐LeRoux, Brahim Heddi, Alexandra Gruss, Jasmina Vidić

This study shows that milk-adapted Staphylococcus aureus is more resistant to reactive oxygen species, antibiotic tolerance, and virulent than serum-adapted strains.

bioRxiv · Oct 31, 2025 · PreprintMicrobiology