Author

Isabel Freund

Technische Universität DarmstadtORCID 0000-0002-5586-1065Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Emilie RenaudiD· 1 shared Florian Frohns· 1 shared Holly ThomasiD· 1 shared Jia-Xuan Chen· 1 shared Jie LiuiD· 1 shared Mareike Haarmann· 1 shared Markus LöbrichiD· 1 shared Wolf‐Dietrich HeyeriD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperCell Biology

Emilie RenaudORCID

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1 paper

Recent·Most cited

Nek family members regulate Rad54 during homologous recombination in developing mice

Isabel Freund, Jie Liu, Holly Thomas, Mareike Haarmann, Emilie Renaud, Florian Frohns, Jia-Xuan Chen, Wolf‐Dietrich Heyer, Markus Löbrich

This study shows that Nek1 regulates Rad54 phosphorylation at Ser572 to promote HR in adult mice but not in embryos, with Nek3 and Nek5 compensating in embryonic cells.

bioRxiv · Dec 22, 2025 · PreprintCell Biology