Zhenfang Wu

Rewiring of 3D chromatin topology orchestrates transcriptional reprogramming in muscle fiber-type specification and transformation

This study identifies how 3D chromatin topology and enhancer-promoter interactions drive transcriptional changes in muscle fiber-type specification and transformation.

Multi-omic characterization of allele-specific regulatory variation in hybrid pigs

This study characterizes allele-specific regulatory variation in hybrid pigs using multi-omic data across tissues and developmental stages, identifying genes influenced by parent-of-origin and genotype effects.

Nucleotide resolution genetic mapping in pigs by publicly accessible whole genome imputation

This study improves genetic mapping resolution in pigs by developing a high-density haplotype reference panel and a public imputation server.

Generation of multi-transgenic pigs using PiggyBac transposons co-expressing pectinase, xylanase, cellulase?β-1.3-1.4-glucanase and phytase

This paper describes the generation of multi-transgenic pigs expressing digestive enzymes to improve feed efficiency and reduce environmental impact.

Establishment of Etv5 gene knockout mice as a recipient model for spermatogonial stem cell transplantation

This study establishes Etv5 gene knockout mice as a recipient model for spermatogonial stem cell transplantation, showing partial success in germ cell restoration but low efficiency in full spermatogenesis.

Genome-wide association analyses of multiple traits in Duroc pigs using low-coverage whole-genome sequencing strategy

The paper uses low-coverage whole-genome sequencing in Duroc pigs to identify SNPs and perform GWAS, finding QTLs for teat number and back fat thickness.