Perttu Permi

Mechanical loading induces distinct and shared responses in endothelial and muscle cells and reveals exercise-like molecular profiles

The paper examines how mechanical loading affects endothelial and muscle cells, revealing shared and distinct molecular responses similar to those seen during exercise.

Prebiotic xylo-oligosaccharides for alleviation of hepatic steatosis: Results from a four-month dietary intervention and determinants of response

This study investigates the effects of xylo-oligosaccharide (XOS) prebiotic on hepatic steatosis in overweight individuals, finding that it reduces harmful gut metabolites and liver fat in responders.

Residual flexibility in the topologically constrained multivalent complex between the GKAP scaffold and LC8 hub proteins

The paper shows that a hexameric complex of GKAP and LC8 proteins has constrained stoichiometry with retained flexibility in the linker region.

Non-invasive peripheral delivery of CDNF fragment protects neurons in models of Parkinsons and ALS

This paper demonstrates that a novel C-CDNF fragment can protect neurons in Parkinson's and ALS models through non-invasive peripheral delivery.

RCD1 Coordinates Chloroplastic and Mitochondrial Electron Transfer through Interaction with ANAC Transcription Factors

The paper shows RCD1 interacts with ANAC transcription factors to regulate chloroplastic and mitochondrial retrograde signaling via ROS-dependent mechanisms.