Author

Alexander C Vostal

National Institutes of HealthORCID 0000-0002-5618-6225Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 3 Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Research Focus:benchmarking· 1 Organism:non-human primate· 1 Research Focus:software / tool· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Jeffrey I. CoheniD· 3 shared Andy A. Patamawenu· 2 shared Anna Hostal· 2 shared Breanna KimiD· 2 shared Ceanna Cooney· 2 shared Dawid MaciorowskiiD· 2 shared Ellison Ober· 2 shared Freya van't VeeriD· 2 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

Jeffrey I. CohenORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

ImmunologybioRxivPreprintMay 17, 2026

Transgene Expression Kinetics and Replication Potential of Recombinant Adenovirus Serotype 4 in a Mouse Model and its Use as a Herpes Simplex Virus Vaccine

Alexander C Vostal, Dawid Maciorowski, James M. Readler…·Jeffrey I. Cohen

This paper evaluates transgene expression and viral replication of recombinant Ad4 in mice, showing protective efficacy against HSV-2 infection.

DOI 10.64898/2026.05.15.725395

mouseexperimental assay

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ImmunologybioRxivPreprintApr 29, 2026

Immunization With Herpes Simplex Virus Nanoparticles Targeting Both Attachment and Fusion Protect Against Infection

Dawid Maciorowski, Alexander C Vostal, Wei Bu…·Jeffrey I. Cohen

This study develops HSV-2 nanoparticles targeting both gD and gH/gL, showing that combined immunization provides robust protection through complementary mechanisms beyond neutralization.

DOI 10.64898/2026.04.24.720674

mousenon-human primate

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ImmunologybioRxivPreprintFeb 5, 2026

Intranasal Replicating Adenovirus type 4-SARS-CoV-2 Recombinants Induce Superior Immune Response Durability and Efficacy in Preclinical Testing Compared to Standard Intramuscular Vaccines

Breanna Kim, Rachel Roenicke, P J Roeder…·Mark Connors

This study compares intranasal and intramuscular vaccines, finding that the intranasal Ad4-S vaccine provides more durable and effective immune responses against SARS-CoV-2 in preclinical models.

1 citation

mouseexperimental assay

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