Modulation of the JAK2-STAT3 pathway promotes expansion and maturation of human iPSCs-derived myogenic progenitor cells
Luca Caputo, Cedomir Stamenkovic, Matthew Timothy Tierney, Alessandra Cecchini, Monica M Nicolau, Gabriele Guarnaccia, Jesus R Barajas, Maria Sofia Falzarano, Rhonda Bassel‐Duby, Alessandra Ferlini, Eric N. Olson, Prem Puri, Alessandra Sacco
The paper shows that modulating the JAK2-STAT3 pathway enhances the yield and maturation of human iPSC-derived myogenic progenitor cells for potential cell therapy.
Stem Cell Reports · Oct 30, 2025Peer-reviewedCell Biology