Alessandra Cecchini

This study identifies SAA1-TLR4 signaling as a tumor-derived pathway driving muscle wasting in pancreatic cancer, showing that targeting this pathway can preserve muscle mass and improve survival without affecting tumor growth.

This study identifies Tenascin-C as a key factor promoting muscle stem cell self-renewal through Annexin A2 signaling, showing its role in muscle repair and aging.

The paper shows that modulating the JAK2-STAT3 pathway enhances the yield and maturation of human iPSC-derived myogenic progenitor cells for potential cell therapy.

This study shows that EphA7 and ephrin-A5 regulate rhabdomyosarcoma proliferation, with ephrin-A5 being a potential therapeutic target for differentiation therapy.