Crystal Sigulinsky

Uncovering the electrical synapse proteome in retinal neurons via in vivo proximity labeling

The paper identifies the proteome of electrical synapses in retinal neurons using BioID in mice and zebrafish, revealing new interactors and their roles in synapse function.

Impact of Aii Amacrine Cell Rewiring in a Pathoconnectome-Based Computational Model of Early Retinal Degeneration

This paper models retinal rewiring in retinitis pigmentosa using pathoconnectomics and predicts altered signaling patterns in Aii amacrine cells.

Expression of Sonic Hedgehog and Pathway Components in the Embryonic Mouse Head: Anatomical Relationships Between Regulators of Positive and Negative Feedback

The paper compares the spatial expression of Sonic Hedgehog and pathway components in the embryonic mouse head to understand context-dependent feedback regulation.

A Pathoconnectome of Early Neurodegeneration

This paper maps the first pathoconnectome in a retina with photoreceptor degeneration, revealing aberrant connectivity and novel synaptic connections.

Heterocellular coupling between amacrine cell and ganglion cells

The paper maps heterocellular coupling between ganglion cells and amacrine cells in the mammalian retina using high-resolution TEM and identifies specific coupling patterns and metabolic interactions.