Alberto E. Pereda

Electrical and chemical synapses share similar organizational principle

The paper investigates the functional organization of electrical synapses in zebrafish, revealing that Cx34.1 is obligatory while Cx34.7 is accessory, with roles defined by the postsynaptic scaffold, similar to chemical synapses.

Uncovering the electrical synapse proteome in retinal neurons via in vivo proximity labeling

The paper identifies the proteome of electrical synapses in retinal neurons using BioID in mice and zebrafish, revealing new interactors and their roles in synapse function.

The components of an electrical synapse as revealed by expansion microscopy of a single synaptic contact

The paper uses expansion microscopy to reveal the structural organization of electrical synapses in zebrafish Mauthner cells, showing multiple gap junctions and their association with adherens junction components.

Neurobeachin controls the asymmetric subcellular distribution of electrical synapse proteins

This study identifies Neurobeachin's role in restricting electrical synapse proteins to dendrites in zebrafish neurons.

A forward genetic screen identifies Dolk as a regulator of startle magnitude through the potassium channel subunit Kv1.1

This study identifies eight genes, including Dolk and Kv1.1, that regulate zebrafish startle behavior through a common genetic pathway, with Dolk affecting Kv1.1 protein localization.

Electrical synaptic transmission requires a postsynaptic scaffolding protein

The paper shows that ZO1, a scaffolding protein, is required for Connexin localization at electrical synapses, which is necessary for functional gap junctions and synaptic transmission.