Granville James Matheson

Building an open infrastructure for molecular neuroimaging: standards and tools from the OpenNeuroPET initiative

The paper describes the OpenNeuroPET initiative, which develops standards and open-source tools to standardize and share PET neuroimaging data, enhancing reproducibility and collaboration.

Building Multivariate Molecular Imaging Brain Atlases Using the NeuroMark PET Independent Component Analysis Framework

The paper introduces NeuroMark PET, an automated framework using spatially constrained ICA to identify Aβ networks in PET data, showing higher sensitivity for age-related changes compared to traditional ROIs.

A Reference Tissue Implementation of Simultaneous Multifactor Bayesian Analysis (SiMBA) of PET Time Activity Curve Data

The paper introduces a reference tissue implementation of SiMBA for PET data analysis, improving parameter estimation accuracy and enabling between-centre data harmonization.

PET Imaging of the Serotonin 1A Receptor in Major Depressive Disorder: Hierarchical Multivariate Analysis of 11CWAY100635 Overcomes Outcome Measure Discrepancies

This study applies hierarchical multivariate analysis to PET data of the serotonin 1A receptor in MDD, showing consistent results across outcome measures and pharmacokinetic models.

Multivariate Analysis of PET Pharmacokinetic Parameters

The paper introduces PuMBA, a multivariate Bayesian method for PET pharmacokinetic analysis, showing improved statistical power and precision compared to univariate methods.

PET-BIDS, an extension to the brain imaging data structure for positron emission tomography

The paper introduces PET-BIDS, an extension of the BIDS standard for PET data, and provides curated datasets and tools for its use.

Low convergent validity of FLB 457

The paper assesses the correlation between [11C]raclopride and [11C]FLB 457 binding potential in extrastriatal brain regions and finds weak to moderate correlations, suggesting caution in using [11C]raclopride for D2-R quantification.

Kinfitr - an open source tool for reproducible PET modelling: validation and evaluation of test-retest reliability

This study validates kinfitr, an open-source R tool for PET kinetic modelling, showing high agreement with the commercial PMOD software in binding estimates and test-retest reliability.

Dopamine D1 receptor availability is not associated with delusional ideation measures of psychosis proneness

The study investigates the association between dopamine D1 receptor availability and delusional ideation in healthy controls using PET and questionnaire data, finding little to no linear association.

kinfitr: Reproducible PET Pharmacokinetic Modelling in R

The paper introduces kinfitr, an R package for reproducible PET pharmacokinetic modelling with 14 kinetic models and tools for data analysis.

We need to talk about reliability: Making better use of test retest studies for study design and interpretation

The paper introduces a method to estimate outcome reliability using test-retest studies to improve study design and avoid underpowered experiments.

Test-retest reliability and convergent validity of (R)-PK11195 outcome measures without arterial input function

This study evaluates test-retest reliability and convergent validity of (R)-[11C]PK11195 binding measures without arterial input function, finding poor reliability and weak correlations for most methods.

Serotonin 5-HT1A receptor binding and self-transcendence in healthy control subjects - a replication study using Bayesian hypothesis testing

This study uses Bayesian hypothesis testing to replicate a previous finding of a link between 5-HT1A receptor binding and self-transcendence traits, finding no significant association.

Is dopamine D1 receptor availability related to social behavior? A positron emission tomography replication study

This study attempts to replicate previous findings linking dopamine D1 receptor availability to social behavior using PET and personality scales but finds no significant correlations.