Development of opioid-induced hyperalgesia depends on reactive astrocytes controlled by Wnt5a signaling
Xin Liu, Chilman Bae, Bolong Liu, Yongmei Zhang, Xiangfu Zhou, Donghang Zhang, Cheng Zhou, Adriana DiBua, Livia Schutz, Martin Kaczocha, Michelino Puopolo, Terry P. Yamaguchi, Jin Mo Chung, Shao‐Jun Tang
This study identifies reactive astrocytes controlled by Wnt5a signaling as critical for opioid-induced hyperalgesia development in mice.
Molecular Psychiatry · Oct 6, 2022Peer-reviewedNeuroscience