cis-eQTL mapping of TB-T2D comorbidity elucidates the involvement of African ancestry in TB susceptibility
Yolandi Swart, Caitlin Uren, Clare Eckold, Jacqueline M. Cliff, Stephanus Theron Malherbe, Katharina Ronacher, Vinod Kumar, Cisca Wijmenga, Hazel M. Dockrell, Reinout van Crevel, Gerhard Walzl, Léanie Kleynhans, Marlo Möller
This study identifies ancestry-specific eQTLs in TB-T2D patients using cis-eQTL mapping, revealing variants associated with gene expression that could guide therapeutic targets in African populations.
bioRxiv · Oct 19, 2022 · PreprintGenetics