Léanie Kleynhans

This study identifies transcriptomic and proteomic features of asymptomatic tuberculosis, revealing distinct sub-clusters and a new blood signature, but finds weaker diagnostic performance for asymptomatic cases compared to symptomatic ones.

The paper identifies gene pathways associated with neutrophil and platelet responses that are activated up to six months before TB diagnosis in whole blood.

This study identifies ancestry-specific eQTLs in TB-T2D patients using cis-eQTL mapping, revealing variants associated with gene expression that could guide therapeutic targets in African populations.