ImmunologybioRxivPreprint
Tumor-specific CD4 T cells cooperate with myeloid cells to remodel the pancreatic tumor microenvironment and enable effective immunotherapy
Eduardo Cruz-Hinojoza, Zoe C. Schmiechen, Sindri M Bonner…·Ingunn M. Stromnes
The paper shows that tumor-specific CD4 T cells, when activated with MHC-II tetramers and anti-CD40, remodel the pancreatic tumor microenvironment to enhance immunotherapy.
DOI 10.64898/2026.07.28.741325