Bacteria hyperpolarize in response to oxygen drop
Maya Peters Kostman, Joshua Girard, Wen Ma, Joseph Larkin
This study shows bacteria hyperpolarize when oxygen levels drop, linking membrane potential to oxygen stress and antibiotic susceptibility.
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Boston UniversityORCID 0000-0002-5660-0246Unclaimed ORCID profile · follow to get notified of new preprints
7 papers
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Maya Peters Kostman, Joshua Girard, Wen Ma, Joseph Larkin
This study shows bacteria hyperpolarize when oxygen levels drop, linking membrane potential to oxygen stress and antibiotic susceptibility.
Ayantika Saha, Joshua M. Jones, Abigail Plummer, Joseph Larkin
This study shows Bacillus subtilis biofilms use polymer composition to drive gel formation and morphological transitions through swelling and cross-linking.
Nicolas A. Ducharme, Joseph Larkin
This study shows that sporulation in Bacillus subtilis biofilms significantly affects viscoelastic properties more than matrix production, enhancing community-level physical stability.
Joshua M. Jones, Meiyi Yao, Andrew Mugler, Joseph Larkin
This study shows that colony expansion and sporulation dynamics in Bacillus subtilis biofilms are interdependent, with sporulation waves driving dormancy while non-sporulating cells maintain expansion.
Jason Samaroo, Abdulrahmen Almodaimegh, Joseph Larkin
This study shows that motile and matrix-producing cells in Bacillus subtilis colonies drive distinct modes of cell-scale motion, with matrix-producing cells causing slow, ballistic movement.
Obadiah Mulder, Maya Peters Kostman, Abdulrahmen Almodaimegh…·Joseph Larkin
This study uses an agent-based model to simulate metabolic signaling oscillations in Bacillus subtilis biofilms, showing how cellular properties drive collective behavior and nutrient distribution.
Joseph T. Incandela, Kangping Hu, Pushkaraj Joshi…·Joseph Larkin
This paper introduces a non-optical, label-free electrical capacitance imaging method to image live microbial samples, enabling spatial and temporal resolution of microbial behavior in diverse environments.