Young‐Gyu Yoon

This paper introduces two photostable voltage sensors, ElectraON and ElectraOFF, which enable longer in vivo recordings by improving photostability compared to existing GEVIs.

This paper develops a red fluorescent calcium indicator, SomaFRCaMPi, which improves neuronal activity imaging accuracy and scale in vivo by reducing neuropil contamination and enhancing signal-to-noise ratio.

This study shows that modifying the optical properties of a mammalian brain can enhance deep imaging without affecting native physiology.

SUPPORT is a self-supervised method that denoises voltage imaging data by leveraging spatiotemporal dependencies, preserving dynamics without requiring action potential information.

This paper demonstrates whole-body expansion microscopy (ExM) for nanoscale imaging of zebrafish larvae and mouse embryos, enabling detailed visualization of anatomical structures and proteins.

PICASSO enables ultra-multiplexed fluorescence imaging of biomolecules through single-round imaging and blind source unmixing, achieving over 15-color multiplexing in various applications.

The paper develops cell body-targeted calcium indicators to improve signal fidelity in one-photon imaging of neural activity in live mice and zebrafish.