Debu Tripathy

This study uses single-cell spatial transcriptomics to show that dendritic cell states and immune architecture in HER2-low breast cancer influence therapeutic response, with specific immune niches linked to resistance or sensitivity.

This study identifies soluble E-cadherin as a driver of brain metastasis in inflammatory breast cancer, showing it promotes tumor survival and metastasis through XIAP-NF-kB activation and reactive astrocytosis.

This paper tests a novel, targeted locoregional therapy for breast cancer liver metastases in mice, showing improved survival and reduced tumor volume.