Yun Xiong

The paper benchmarks nDIA and related proteomics methods, showing nDIA with DIA-NN and Tesorai Search provides high coverage and reliable results in proteomic analysis.

This study identifies soluble E-cadherin as a driver of brain metastasis in inflammatory breast cancer, showing it promotes tumor survival and metastasis through XIAP-NF-kB activation and reactive astrocytosis.

This study shows that disrupting the WRAD core in pancreatic cancer leads to DNA replication errors, immune response activation, and improved response to immune checkpoint inhibitors.

The paper introduces UFP-MS, a fast proteomics method, and applies it to study drug effects on mouse tissues, revealing tissue-specific metabolic changes.

The paper identifies 437 human proteins interacting with SARS-CoV-2 and compares interactomes of NSP1 and N protein with related coronaviruses to reveal common and divergent host pathways.