Author

Nathalia Graf Grachet

University of ArizonaORCID 0000-0002-5713-8065Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 2 Approach:statistical model· 2 Research Focus:database / resource· 1 Research Focus:dimensionality reduction· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:metabolomics· 1

Frequent Co-Authors

A. SkanderupiD· 1 shared Aaron TaniD· 1 shared Andrea Teh Xin Yi· 1 shared Anna GaniD· 1 shared Avril Lim· 1 shared Christian Ayala-OrtiziD· 1 shared Cristina Howard‐VaronaiD· 1 shared D SW Shao-Weng TaniD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperBioinformatics

A. SkanderupORCID

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2 papers

Recent·Most cited

Systematic benchmarking of multi-modal approaches for tumor-naive ctDNA detection and quantification

Ting Qi, Denis Odinokov, Lakshmi Narayanan Lakshmanan, Nathalia Graf Grachet, Melanie Lou, Seng Lor Saelee, Gladys Garcia-Montoya, Pui Mun Wong, Rafeed Chowdhury Rahman, Hosseinali Asgharian, Andrea Teh Xin Yi, Nicole Hnin Ye Pyone, Lan Ying Wang, Guat Tin Tan, Hanaé Carrié, , A. Skanderup

This study benchmarks tumor-naive ctDNA detection and quantification methods using WGS and methylation data from cancer patients, identifying performance trade-offs and optimal integration strategies.

bioRxiv · Jun 24, 2026 · PreprintBioinformatics

MetaboDirect: An Analytical Pipeline for the processing of FTICR-MS-based Metabolomics Data

Christian Ayala-Ortiz, Nathalia Graf Grachet, Viviana Freire-Zapata, Jane Fudyma, Gina Hildebrand, Roya AminiTabrizi, Cristina Howard‐Varona, Yuri Corilo, Nancy J. Hess, Melissa Beth Duhaime, Matthew B. Sullivan, Malak Tfaily

MetaboDirect is an open-source pipeline for processing FTICR-MS metabolomics data, offering automated analysis, visualization, and biochemical network generation.

Microbiome · Feb 17, 2023Peer-reviewedBioinformatics