Author

Fabrizio Capitano

Centre National de la Recherche ScientifiqueORCID 0000-0002-5718-4002Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:mouse· 2 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:electronic health records· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Massimo MantegazzaiD· 2 shared Elisabetta MennaiD· 1 shared Evgeniia Rusina· 1 shared Flavia AntonucciiD· 1 shared G FossatiiD· 1 shared Hava ChaptoukaeviD· 1 shared Isabelle LénaiD· 1 shared Jennifer LavigneiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersNeuroscience

Massimo MantegazzaORCID

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2 papers

Recent·Most cited

Neurodevelopmental defects in Dravet syndrome Scn1a+/- mice: targeting GABA-switch rescues behavioral dysfunctions but not seizures and mortality.

Lara Pizzamiglio, Fabrizio Capitano, Evgeniia Rusina, G Fossati, Elisabetta Menna, Isabelle Léna, Flavia Antonucci, Massimo Mantegazza

Neurobiology of Disease · Feb 26, 2025Peer-reviewedNeuroscience

Preictal dysfunctions of inhibitory interneurons paradoxically lead to their rebound hyperactivity and to Low-Voltage-Fast onset seizures in Dravet syndrome.

Fabrizio Capitano, Mathieu Kuchenbuch, Jennifer Lavigne, Hava Chaptoukaev, María A. Zuluaga, Marco Lorenzi, Rima Nabbout, Massimo Mantegazza

The paper investigates seizure mechanisms in Dravet syndrome, finding that preictal dysfunctions of inhibitory interneurons lead to rebound hyperactivity and low-voltage-fast seizures.

Proceedings of the National Academy of Sciences · May 29, 2024Peer-reviewedNeuroscience