Author

Lucia Casadei

The Ohio State University Wexner Medical CenterORCID 0000-0002-5731-8197Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Abeba ZewduiD· 1 shared Danielle BraggioiD· 1 shared David Koller· 1 shared David WangiD· 1 shared Dawn S. ChandleriD· 1 shared Denis C. Guttridge DiD· 1 shared Fernanda Costas Casal de FariaiD· 1 shared Gonzalo LopeziD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Abeba ZewduORCID

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1 paper

Recent·Most cited

Molecular BiologyPLoS ONEPeer-reviewedSep 17, 2025

Blockade of Interleukin-6 (IL-6) Signaling in Dedifferentiated Liposarcoma (DDLPS) Decreases Mouse Double Minute 2 (MDM2) Oncogenicity via Alternative Splicing

Abeba Zewdu, Danielle Braggio, Gonzalo Lopez…·Raphael E. Pollock

This study shows that blocking IL-6 signaling in DDLPS reduces MDM2 oncogenicity through alternative splicing, suggesting a potential therapeutic target.

2 citations

mousebulk RNA-seq

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