Author

David Koller

The Ohio State University Wexner Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Abeba ZewduiD· 1 shared Danielle BraggioiD· 1 shared David WangiD· 1 shared Dawn S. ChandleriD· 1 shared Denis C. Guttridge DiD· 1 shared Fernanda Costas Casal de FariaiD· 1 shared Gonzalo LopeziD· 1 shared Hemant Kumar Bid· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Abeba ZewduORCID

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1 paper

Recent·Most cited

Blockade of Interleukin-6 (IL-6) Signaling in Dedifferentiated Liposarcoma (DDLPS) Decreases Mouse Double Minute 2 (MDM2) Oncogenicity via Alternative Splicing

Abeba Zewdu, Danielle Braggio, Gonzalo Lopez, Kara Batte, Safiya Khurshid, Fernanda Costas Casal de Faria, Hemant Kumar Bid, David Koller, Lucia Casadei, Katherine J. Ladner, David Wang, Valerie Patrice Grignol, Obiajulu Hans Iwenofu, Dawn S. Chandler, Denis C. Guttridge D, Raphael E. Pollock

This study shows that blocking IL-6 signaling in DDLPS reduces MDM2 oncogenicity through alternative splicing, suggesting a potential therapeutic target.

PLoS ONE · Sep 17, 2025Peer-reviewedMolecular Biology