Author

Kat Moore

Amsterdam UMC Location University of AmsterdamORCID 0000-0002-5746-4098Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Approach:benchmark study· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

Alexander B. MeijeriD· 2 shared Floris P. J. van Alphen· 2 shared Marieke v. LinderniD· 2 shared Nurcan YağcıiD· 2 shared Peter A.C. ’t HoeniD· 2 shared Anna G. ManjóniD· 1 shared Daniël J. VisiD· 1 shared Emile van den AkkeriD· 1 shared

Activity by Year

2017-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersMolecular Biology

Alexander B. MeijerORCID

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3 papers

Recent·Most cited

Predicting clinical drug response from model systems by non-linear subspace-based transfer learning

Soufiane M. C. Mourragui, Marco Loog, Daniël J. Vis, Kat Moore, Anna G. Manjón, Mark A. van de Wiel, Marcel J. T. Reinders, Lodewyk F.A. Wessels

The paper develops TRANSACT, a transfer learning framework for predicting clinical drug response, outperforming existing methods on multiple datasets.

Proceedings of the National Academy of Sciences · Dec 3, 2021Peer-reviewedBioinformatics

Csde1 binds transcripts involved in protein homeostasis and controls their expression in erythropoiesis

Kat Moore, Nurcan Yağcı, Floris P. J. van Alphen, Nahuel A. Paolini, Rastislav Horos, Ntsiki M. Held, Riekelt H. Houtkooper, Emile van den Akker, Alexander B. Meijer, Peter A.C. ’t Hoen, Marieke v. Lindern

This study identifies Csde1-bound transcripts in erythropoiesis and shows that Csde1 regulates their expression through effects on mRNA stability and translation.

Scientific Reports · Feb 2, 2018Peer-reviewedMolecular Biology

Csde1 cooperates with Strap to control translation of erythroid transcripts

Kat Moore, Nurcan Yağcı, Floris P. J. van Alphen, Alexander B. Meijer, Peter A.C. ’t Hoen, Marieke v. Lindern

This study identifies Strap as a key partner of Csde1 in erythroblasts, showing that their complex regulates the translation of transcripts critical for erythropoiesis and hypoxia response.

bioRxiv · Oct 23, 2017 · PreprintMolecular Biology