Author
University of SheffieldORCID 0000-0002-5776-7240Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Monika A. Myszczynska, Matthew J. Stopford, Nóra M. Márkus…·Laura Ferraiuolo
This paper uses AI to identify gefitinib as a potential ALS treatment, showing it protects motor neurons and reduces TDP-43 fragments in vitro and in vivo.
Amy F. Keerie, Raquel Rua Martins, Chloe F. Allen…·Richard J. Mead
M102, a dual NRF2/HSF1 activator, slows disease progression in 2 mouse models and exerts neuroprotection in human cellular models of ALS.
Scott McKinnon, Zekai Qiang, Amy F. A. Keerie…·Richard J. Mead
This study compares compound muscle action potentials (CMAPs) in SOD1G93A mice and human ALS patients to identify translational alignment points for disease progression.