Amanda Mercedes Jamieson

Aspartic proteases are abundant and active in acidified wound fluid

This study identifies aspartic proteases as active enzymes in acidified wound fluid, showing their activity is optimal between pH 3.0 and 3.8 and persists for ten days post-injury.

Peripheral CaV2.2 channels in skin regulate prolonged heat hypersensitivity during neuroinflammation

This study shows that peripheral CaV2.2 channels in skin are critical for heat hypersensitivity during chronic neuroinflammation but not for mechanical hypersensitivity or edema.

Machine Learning Assisted Spectral Fingerprinting for Immune Cell Phenotyping

This paper uses NIR fluorescence and Raman microscopy combined with machine learning to identify macrophage phenotypes based on DNA-SWCNT interactions, achieving >95% accuracy.

Interleukin-1α links peripheral CaV2.2 channel activation to rapid adaptive increases in heat sensitivity in skin

This study identifies interleukin-1 as the key cytokine mediating rapid adaptive increases in heat and mechanical sensitivity in skin following capsaicin exposure.