Aidan Kindopp

This paper develops a nanoparticle platform to target TLR3 agonist to antigen-presenting cells, improving cancer immunotherapy safety and efficacy by reducing systemic toxicity and enhancing tumor targeting.

This paper develops a multivalent peptide-polymer conjugate that mimics STING to activate innate immune signaling and shows tumor regression in ovarian cancer models.

The paper shows that anionic polypeptide coatings on nanoparticles bind to cancer-associated amino acid transporters, enabling targeted drug delivery through electrostatic interactions and transporter clustering.

This study improves the stability and reconstitution of DNA-functionalized carbon nanotubes using lyophilization with cryoprotectants, enhancing their performance in biomedical applications.

This paper uses NIR fluorescence and Raman microscopy combined with machine learning to identify macrophage phenotypes based on DNA-SWCNT interactions, achieving >95% accuracy.