BioinformaticsNucleic Acids ResearchPeer-reviewed
Regulatory elements can be essential for maintaining broad chromatin organization and cell viability
Ying Liu, Bo Ding, Lina Zheng…·Wensheng Wei
The paper identifies essential regulatory elements that maintain chromatin organization and cell viability through their role in 3D chromatin contacts, showing that non-essential genes can synergize to cause cell death.
6 citations