Ping Xu

Regulatory elements can be essential for maintaining broad chromatin organization and cell viability

The paper identifies essential regulatory elements that maintain chromatin organization and cell viability through their role in 3D chromatin contacts, showing that non-essential genes can synergize to cause cell death.

Non-coding loci without epigenomic signals can be essential for maintaining global chromatin organization and cell viability

The paper identifies non-coding genomic regions critical for chromatin organization and cell viability, showing their structural importance despite lacking epigenomic signals or annotated elements.

5' Modifications Improve Potency and Efficacy of DNA Donors for Precision Genome Editing

This study shows that 5' modifications to DNA repair templates enhance precision genome editing efficiency in multiple animal models and human cells.

Sulforaphane modulates microRNA expression in colon cancer cells to implicate the regulation of oncogenes CDC25A, HMGA2 and MYC

This study investigates how sulforaphane affects microRNA expression in colon cancer and non-cancer cells, identifying potential targets like CDC25A, HMGA2, and MYC.