Miki Bundo

This study shows that genetic and epigenetic regulation of SLC6A4 influences vulnerability to cognitive decline and depressive symptoms in older adults.

The paper examines the association between Alzheimer's disease polygenic risk scores and cognitive decline measured by MMSE in a Japanese cohort, finding stronger associations with scores derived from Japanese GWAS.

This study shows that hepatic ketogenesis reduces cardiac hypertrophy in HFpEF by maintaining beta-hydroxybutyrate levels, which modulate myocardial metabolism.

The paper maps sex-associated DNA methylation in blood cell types using whole genome bisulfite sequencing data from the iMETHYL database, identifying cell-type specific differentially methylated sites and their functional implications.

The paper identifies hypermethylation of SLC6A4 in male schizophrenia patients and links it to reduced amygdala volume and 5-HTTLPR genotype.