Author

Yuichiro Arima

Center for Metabolic Regulation of Healthy Aging, Kumamoto UniversityORCID 0000-0002-9840-3347Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Neuroscience· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:metabolism & bioenergetics· 1 Assay:spatial transcriptomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Eiichiro YamamotoiD· 2 shared Kei MorikawaiD· 2 shared Kenichi TsujitaiD· 2 shared Shinsuke HanataniiD· 2 shared Takumi Nagakura· 2 shared Yasuhiro IzumiyaiD· 2 shared Akira Fujiyama· 1 shared Chitoku TodaiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersPhysiology

Eiichiro YamamotoORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

IL-17A Mediates Cardiac Hypertrophy in Chronic Kidney Disease through the IL-23/Th17 Axis.

Fumihiko Ogata, Shinsuke Hanatani, Yuki Okuno, Masahiro Yamamoto, Kei Morikawa, Takumi Nagakura, Satoshi Araki, Eiichiro Yamamoto, Yuichiro Arima, Yasuhiro Izumiya, Kenichi Tsujita

This study shows that IL-17A promotes cardiac hypertrophy in CKD via the IL-23/Th17 axis, with IL-12p40 as a potential biomarker and therapeutic target.

bioRxiv · Sep 23, 2026 · PreprintPhysiology

Hepatic Ketogenesis Attenuates Cardiac Hypertrophy via Metabolic Reprogramming

Toshihiro Yamada, Kei Morikawa, Akira Fujiyama, Takumi Nagakura, Yuqing Xu, Miho Kataoka, Terumasa Umemoto, Miki Bundo, Kazuya Iwamoto, Zeeshan Ahmed, Suvi Linna-Kuosmanen, Shinsuke Hanatani, Hiroki Usuku, Yasushi Matsuzawa, Yasuhiro Izumiya, , Yuichiro Arima

This study shows that hepatic ketogenesis reduces cardiac hypertrophy in HFpEF by maintaining beta-hydroxybutyrate levels, which modulate myocardial metabolism.

bioRxiv · Feb 2, 2026 · PreprintBiochemistry

Hypothalamic prostaglandins facilitate recovery from hypoglycemia but exacerbate recurrent hypoglycemia in mice

Takashi Abe, Shucheng Xu, Yuki Sugiura, Yuichiro Arima, Takahiro Hayasaka, Ming‐Liang Lee, Taiga Ishimoto, Yudai Araki, Samson Ngurari, Ziwei Niu, Norifumi Iijima, Sabrina Diano, Chitoku Toda

This study investigates the role of hypothalamic prostaglandins in glucose recovery during acute hypoglycemia and recurrent hypoglycemia in mice, finding that they enhance recovery but impair counter-regulatory responses during recurrence.

bioRxiv · Jun 24, 2024 · PreprintNeuroscience