GeneticsGenes & DevelopmentPeer-reviewed
HELLS and PRDM9 form a Pioneer Complex to Open Chromatin at Meiotic Recombination Hotspots
Catrina A. Spruce, Sibongakonke Dlamini, Guruprasad Ananda…·Christopher L. Baker
The paper shows HELLS and PRDM9 form a pioneer complex to open chromatin at meiotic recombination hotspots, enabling DSB machinery access and preventing sterility in male mice.