Defective synapse maturation and enhanced synaptic plasticity in Shank2-/- mice
Stephanie Wegener, Arne Buschler, A. Vanessa Stempel, SukJae Joshua Kang, Chae‐Seok Lim, Bong‐Kiun Kaang, Sarah A. Shoichet, Denise Manahan‐Vaughan, Dietmar Schmitz
This study shows Shank2-/- mice have defective synapse maturation and enhanced synaptic plasticity, providing a mechanistic explanation for increased long-term potentiation.
eNeuro · May 1, 2018Peer-reviewedNeuroscience