Author

Ellen M. Olzomer

UNSW SydneyORCID 0000-0002-5823-0736Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Andrew John BrowniD· 1 shared Frances L. ByrneiD· 1 shared Hongyuan YangiD· 1 shared Hudson W. CoatesiD· 1 shared Isabelle M. Capell-HattamiD· 1 shared Rhonda FarrelliD· 1 shared Ximing DuiD· 1 shared

Activity by Year

2022-2022 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperMolecular Biology

Andrew John BrownORCID

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1 paper

Recent·Most cited

Hypoxia truncates and constitutively activates the key cholesterol synthesis enzyme squalene monooxygenase

Hudson W. Coates, Isabelle M. Capell-Hattam, Ellen M. Olzomer, Ximing Du, Rhonda Farrell, Hongyuan Yang, Frances L. Byrne, Andrew John Brown

The paper shows hypoxia triggers truncation and constitutive activation of squalene monooxygenase (SM) through proteasomal targeting and substrate accumulation, linking it to oncogenic properties in endometrial cancer.

eLife · Dec 13, 2022Peer-reviewedMolecular Biology