Nuclear lamina-associated domain biogenesis is regulated by nuclear pore density during embryogenesis and mediates UV protection
Fei Xu, Adrián Fragoso-Luna, Itai Sharon, Angelo Luiz Angonezi, Ohad Medalia, Peter Askjaer, Susan E. Mango
The paper shows that nuclear pore density regulates LAD formation during C. elegans embryogenesis, with heterochromatic LADs providing UV protection.
bioRxiv · Oct 1, 2025 · PreprintDevelopmental Biology