Author

Pedro Ozório Brum

Institute of Molecular BiotechnologyORCID 0000-0002-5858-8017Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Animal Behavior & Cognition· 1 Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1

Frequent Co-Authors

Federico ScaramuzzaiD· 2 shared Kristin Tessmar‐RaibleiD· 2 shared Andrew S. I. LoudoniD· 1 shared Anita NavidiD· 1 shared Arthur Bandeira de Mello GarciaiD· 1 shared Audrey M. MatiD· 1 shared Ava Abdi· 1 shared Birgit Poehn· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersAnimal Behavior & Cognition

Federico ScaramuzzaORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Animal Behavior & CognitionbioRxivPreprintOct 20, 2026

A circalunar oscillator and moonlight tune the circadian clock to moon phase via cwo/Dec1

Federico Scaramuzza, Gabriele Andreatta, Audrey M. Mat…·Kristin Tessmar‐Raible

This study identifies cwo/Dec1 as a molecular mechanism linking the circadian clock to lunar phase in Platynereis dumerilii, showing its role in circalunar oscillation.

DOI 10.64898/2026.10.14.757926

mousebulk RNA-seq

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Cell BiologybioRxivPreprintSep 17, 2026

PER2- and state-dependent transcriptional programs gate neural stem cell proliferation with niche-specific circadian autonomy

Pedro Ozório Brum, Ava Abdi, Federico Scaramuzza…·Noelia Urbán

The paper shows PER2-dependent circadian regulation of adult neural stem cell proliferation in two niches, with SVZ requiring external stimuli for synchronization.

DOI 10.64898/2026.09.14.751519

mousebulk RNA-seq

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Molecular BiologybioRxivPreprintAug 11, 2026

Metformin modulates autophagy in heterozygous and CRISPR-edited TSC2 primary fibroblasts

Guilherme Danielski Viola, Pedro Ozório Brum, Arthur Bandeira de Mello Garcia…·Clévia Rosset

This study shows that metformin restores autophagy in TSC2 haploinsufficient and CRISPR-edited fibroblasts by blocking mTORC1, suggesting a potential therapeutic strategy for TSC.

DOI 10.64898/2026.08.11.743350

humanexperimental assay

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