Andrew S. I. Loudon

The paper shows PER2-dependent circadian regulation of adult neural stem cell proliferation in two niches, with SVZ requiring external stimuli for synchronization.

The paper quantifies circadian interactions and protein abundance to reveal mechanisms maintaining the circadian clock's operational stability.

This study shows HNF4A is essential for liver-specific GR action, with HNF4A regulating GR binding sites and transcriptional response to glucocorticoids in the liver.

This study uses single-nuclei RNAseq to analyze Atlantic salmon gill during smoltification, identifying 20 cell clusters and showing immune reprogramming associated with seawater transfer.

This study identifies the circadian clock mechanism in mammals that drives seasonal responses to photoperiod changes through BMAL2 and EYA3/TSH pathways.

The paper presents a high-quality quail genome and uses it to study social behavior, photoperiodism, and immune response to H5N1 influenza.

The paper re-evaluates the efficiency of a CRISPR-Cas9 method for generating conditional knockout alleles in mice, finding very low success rates and high rates of undesired alleles.

This study identifies 42 genetic loci associated with excessive daytime sleepiness and links them to phenotypic subgroups and related traits.

The paper identifies 57 genomic regions associated with insomnia symptoms, linking them to phototransduction, ubiquitination, and potential causal relationships with coronary heart disease and depression.

This study identifies new genetic loci associated with sleep disturbance traits and finds shared genetic links with neuropsychiatric and metabolic traits.