Author

Julia F. Charles

Brigham and Women's HospitalORCID 0000-0002-5875-314XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:experimental assay· 2 Research Focus:development & morphogenesis· 1 Approach:statistical model· 1

Frequent Co-Authors

Jessica A. LehoczkyiD· 2 shared Anika ShimontyiD· 1 shared Dyann SegvichiD· 1 shared Elissa ZboinskiiD· 1 shared Emily McDonald· 1 shared Gemma L. JohnsoniD· 1 shared Jeffrey W. Duryea· 1 shared Joseph M. WallaceiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersDevelopmental Biology

Jessica A. LehoczkyORCID

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3 papers

Recent·Most cited

Site-, strain- and mutation-specific osteopetrosis phenotypes in mice with Clcn7 variants

Anika Shimonty, Xenia G Dahl, Elissa Zboinski, Dyann Segvich, Kelly Tsang, Emily McDonald, Joseph M. Wallace, Thomas L. Andersen, Julia F Charles

This study examines how Clcn7 mutations in mice affect bone phenotypes, showing increased trabecular bone mass with variations based on age, sex, genetic background, and mutation type.

bioRxiv · Nov 4, 2026 · PreprintPhysiology

En1 and Lmx1b do not recapitulate embryonic dorsal-ventral limb patterning functions during mouse digit tip regeneration

Gemma L. Johnson, Morgan B. Glasser, Julia F. Charles, Jeffrey W. Duryea, Jessica A. Lehoczky

This study investigates whether En1 and Lmx1b, which are critical for DV patterning during limb development, also regulate DV patterning during mouse digit tip regeneration, finding they do not.

Cell Reports · Nov 1, 2022Peer-reviewedDevelopmental Biology

LGR6 is necessary for attaining peak bone mass and regulates osteogenesis through differential ligand use

Vikram Khedgikar, Julia F. Charles, Jessica A. Lehoczky

This study shows LGR6 is essential for osteoblast proliferation, differentiation, and peak bone mass, with distinct signaling roles for its ligands RSPO2 and MaR1.

Bone · Nov 30, 2021Peer-reviewedDevelopmental Biology