Thomas Levin Andersen

Site-, strain- and mutation-specific osteopetrosis phenotypes in mice with Clcn7 variants

This study examines how Clcn7 mutations in mice affect bone phenotypes, showing increased trabecular bone mass with variations based on age, sex, genetic background, and mutation type.

Restoring oxidative phosphorylation enhances osteogenesis in mitochondrial DNA translation defective human bone marrow stromal cells

Metastatic infiltration of nervous tissue and periosteal nerve sprouting in multiple myeloma induced bone pain

This study identifies periosteal nerve sprouting and DRG metastasis in MM-induced bone pain, linking these changes to pain mechanisms and suggesting neuroprotective strategies.

FIBCD1 is a Conserved Receptor for Chondroitin Sulphate Proteoglycans of the Brain Extracellular Matrix and a Candidate Gene for a Complex Neurodevelopmental Disorder

This study identifies FIBCD1 as a conserved receptor for chondroitin sulphate proteoglycans in the brain ECM, linking it to neurodevelopmental disorders through genetic and functional analyses.

Bone innervation and vascularization regulated by osteoclasts contribute to refractive pain-related behavior in the collagen antibody-induced arthritis model

This study shows osteoclasts contribute to pain in arthritis by affecting bone vascularization and innervation, and inhibitors can reverse this pain.

High-throughput RNA sequencing from paired lesional- and non-lesional skin reveals major alterations in the psoriasis circRNAome

This study uses RNA-seq to compare circRNA expression in lesional and non-lesional psoriasis skin, finding reduced circRNA abundance without clear links to miRNA binding site changes.