The gamma-butyrolactone receptors ScbR and AtrA form a quorum sensing switch between coelimycin and actinorhodin synthesis in Streptomyces coelicolor A3(2)
Bartosz Bednarz, Magdalena Kotowska, Mateusz Wenecki…·Krzysztof Pawlik
The paper identifies AtrA as a GBL receptor that activates coelimycin production while repressing actinorhodin, revealing a quorum sensing mechanism for antibiotic synthesis in Streptomyces coelicolor.