Author

Sophie Torrekens

KU LeuvenORCID 0000-0002-5900-0481Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Bram VandewinkeliD· 1 shared Els HenckaertsiD· 1 shared Mathieu BolleniD· 1 shared Zander ClaesiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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1 shared paperCell Biology

Bram VandewinkelORCID

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1 paper

Recent·Most cited

The adeno-associated virus Rep proteins target PP4:SMEK1 by preventing substrate-recruitment

Bram Vandewinkel, Sophie Torrekens, Zander Claes, Mathieu Bollen, Els Henckaerts

This study identifies PP4:SMEK1 as a host restriction factor suppressed by AAV Rep proteins through substrate-recruitment interference, enhancing rAAV vector potency.

PLoS Pathogens · Mar 10, 2026Peer-reviewedCell Biology