Author

Bram Vandewinkel

KU LeuvenORCID 0000-0002-8534-8334Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

Celien LismontiD· 1 shared Cláudio F. CostaiD· 1 shared Dorien ImberechtsiD· 1 shared Els HenckaertsiD· 1 shared Hans R. WaterhamiD· 1 shared Hongli LiiD· 1 shared Jorge E. AzevedoiD· 1 shared Marc FranseniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCell Biology

Celien LismontORCID

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2 papers

Recent·Most cited

The adeno-associated virus Rep proteins target PP4:SMEK1 by preventing substrate-recruitment

Bram Vandewinkel, Sophie Torrekens, Zander Claes, Mathieu Bollen, Els Henckaerts

This study identifies PP4:SMEK1 as a host restriction factor suppressed by AAV Rep proteins through substrate-recruitment interference, enhancing rAAV vector potency.

PLoS Pathogens · Mar 10, 2026Peer-reviewedCell Biology

PEX14 functions as a molecular link between optineurin and pexophagy in human cells

Hongli Li, Suyuan Chen, Celien Lismont, Bram Vandewinkel, Mohamed A. F. Hussein, Cláudio F. Costa, Dorien Imberechts, Yiyang Liu, Jorge E. Azevedo, Wim Vandenberghe, Steven H. L. Verhelst, Hans R. Waterham, Pieter Vanden Berghe, Myriam I Baes, Marc Fransen

This study identifies PEX14 as a molecular link between optineurin and pexophagy, elucidating its role in recruiting autophagic machinery for peroxisome degradation.

The Journal of Cell Biology · Aug 14, 2025Peer-reviewedCell Biology