Johannes R. Hov

The paper identifies ultra long-lived plasma cells in the human small intestine that produce IgA antibodies reactive to a diverse microbiota, suggesting long-term immune memory shaping the microbiome.

The paper profiles T cell receptor alpha repertoires in IBD patients across multiple cohorts, identifies disease-associated clonotypes, and validates findings in an independent dataset.

The paper identifies and validates T cell receptor clonotypes associated with Crohn's disease and ulcerative colitis, suggesting they are potential therapeutic targets.

The paper identifies three metabolic at-risk profiles in HIV-treated patients using multi-omics integration, highlighting dysregulated metabolism and microbiome interactions.

This study examines how a major genetic risk factor for COVID-19 affects mortality and severity, finding stronger effects in younger adults.