Gloria Rita Bertoli

Disrupting Pregnane X Receptor Signaling Overcomes Temozolomide Resistance in Glioblastoma via Succisa pratensis-Derived Metabolites

This paper shows that Succisa pratensis enhances temozolomide efficacy in glioblastoma by inducing metabolic vulnerability and impairing PXR signaling.

Chronic pain alters microvascular architectural organization of somatosensory cortex

This study identifies microvascular neogenesis in somatosensory cortex of chronic pain models, suggesting altered vascular architecture with potential implications for CP diagnosis and treatment.

Removal of behavioural and electrophysiological signs of chronic pain by in vivo microsections of rat somatosensory cortex with parallel X-ray microbeams

The paper investigates the removal of chronic pain signs in rats using X-ray microbeam irradiation to disrupt and restore cortical network properties.

Identification of microRNA clusters cooperatively acting on Epithelial to Mesenchymal Transition in Triple Negative Breast Cancer

The paper identifies miRNA clusters driving triple negative breast cancer subtypes using a new computational pipeline and validates their role in promoting the phenotype through proliferation and EMT control.

Moonlight: a tool for biological interpretation and driver genes discovery

Moonlight identifies cancer driver genes and their roles by integrating functional analysis and gene regulatory networks from expression data, distinguishing tumor suppressors, oncogenes, and moonlight genes.