Peter Radermacher

Intubation and mechanical ventilation lead to an extensive expansion of VAP-associated bacterial species in respiratory secretions of ventilated pigs

This study shows that intubation and mechanical ventilation in pigs leads to a significant increase in Gram-negative bacteria in respiratory secretions above the cuff, which may contribute to VAP development.

Intracranial hypertension drives astrocyte-mediated neuroinflammation through Piezo1-dependent EGFR activation

This study identifies a mechanosensitive astrocyte signaling pathway linking intracranial pressure to neuroinflammation via Piezo1-dependent EGFR activation.

Bayesian 13C-metabolic flux analysis of parallel tracer experiments in granulocytes: A directional shift within the non-oxidative pentose phosphate pathway supports phagocytosis

The paper uses Bayesian 13C-metabolic flux analysis to show phagocytosis reverses non-oxidative PPP flux direction in granulocytes.