Author

Enrico Calzia

University Hospital UlmORCID 0000-0003-2663-9147Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Neuroscience· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Alessandro Ori‬‬iD· 1 shared Andrea HoffmanniD· 1 shared Arne SahmiD· 1 shared Besnik Muqaku· 1 shared Burak ÖzkaniD· 1 shared Fabrice A. C. KleiniD· 1 shared Fan SuniD· 1 shared Florian Olde HeuveliD· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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1 shared paperSystems Biology

Alessandro Ori‬‬ORCID

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3 papers

Recent·Most cited

Molecular BiologybioRxivPreprintJul 7, 2026

The huntingtin-HAP40 complex is a bidirectional cellular rheostat

Manuel Seefelder, Fabrice A. C. Klein, Enrico Calzia…·Stefan Kochanek

The paper shows the HTT-HAP40 complex acts as a bidirectional rheostat regulating stress response and lipid metabolism, with loss of balance linked to Huntington's disease pathogenesis.

DOI 10.64898/2026.06.03.729778

humanproteomics

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NeurosciencebioRxivPreprintMay 2, 2025

Intracranial hypertension drives astrocyte-mediated neuroinflammation through Piezo1-dependent EGFR activation

Zongren Zhao, Andrea Hoffmann, Fan Sun…·Marica Pagliarini

This study identifies a mechanosensitive astrocyte signaling pathway linking intracranial pressure to neuroinflammation via Piezo1-dependent EGFR activation.

DOI 10.1101/2025.05.02.651431

humanexperimental assay

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Systems BiologyBMC BiologyPeer-reviewedJul 27, 2018

Species comparison of liver proteomes reveals links to naked mole-rat longevity and human aging.

Ivonne Heinze, Martin Bens, Enrico Calzia…·Alessandro Ori‬‬

The paper compares liver proteomes of long-lived naked mole-rats and short-lived guinea pigs to identify molecular networks linked to longevity and human aging.

65 citations

proteomicsstatistical model

𝕏 PostBluesky