Intubation and mechanical ventilation lead to an extensive expansion of VAP-associated bacterial species in respiratory secretions of ventilated pigs
Lara Spring, Dorina Haider, Andrea Hoffmann, Fabian Zink, Martin Heßling, Peter Radermacher, Franziska Münz, Ohad Sharon, Magnus Scheer, Maximilian Feth, Thomas Kapapa, Barbara Spellerberg
This study shows that intubation and mechanical ventilation in pigs leads to a significant increase in Gram-negative bacteria in respiratory secretions above the cuff, which may contribute to VAP development.
bioRxiv · Oct 14, 2026 · PreprintMicrobiology